Dexlansoprazole (brand name Dexilant) is a proton pump inhibitor (PPI) widely prescribed to manage acid-related conditions such as gastroesophageal reflux disease (GERD) and erosive esophagitis.
This article will help you understand its uses, side effects, precautions, and other important details to help you make informed decisions about its use.
- Key Details of Dexlansoprazole
- What Is Dexlansoprazole and How Does It Work?
- How to Take Dexlansoprazole
- Recommended Dosage
- Side Effects of Dexlansoprazole
- Common Side Effects
- Serious Side Effects
- Precautions and Warnings
- Who Should Avoid Dexlansoprazole?
- Drug Interactions
- How to Store Dexlansoprazole
- What Should You Do If You Miss a Dose or Overdose?
- Missed Dose
- Overdose
- Conclusion
- People May Ask
- 1. How long does it take for Dexlansoprazole to work?
- 2. Can Dexlansoprazole be taken during pregnancy?
- 3. What should I do if I miss a dose?
- 4. Can Dexlansoprazole cause bone problems?
- 5. Is it safe to drink alcohol while taking Dexlansoprazole?
- Disclaimer
Key Details of Dexlansoprazole
| Aspect | Details |
| Generic Name | Dexlansoprazole |
| Brand Names | Dexilant, Kapidex |
| Drug Class | Proton pump inhibitor (PPI) |
| Common Uses | GERD, erosive esophagitis, and other acid-related conditions |
| Available Forms | 30 mg, 60 mg delayed-release capsules |
| Prescription Requirement | Yes, prescription only |
| Side Effects | Diarrhea, nausea, headache, stomach pain, severe allergic reactions |
| Storage | Store at room temperature (20°C to 25°C) |
| Pregnancy Category | Consult your doctor if pregnant or breastfeeding |
| Drug Interactions | May interact with methotrexate, warfarin, digoxin, and HIV medications |
What Is Dexlansoprazole and How Does It Work?
Dexlansoprazole is primarily used to reduce excessive stomach acid production, which helps alleviate symptoms like heartburn, acid reflux, and damage to the esophagus caused by acid.
It works by blocking proton pumps in the stomach that are responsible for producing stomach acid, thereby offering relief for individuals suffering from acid-related digestive conditions,
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Common Uses of Dexlansoprazole
Dexlansoprazole is prescribed for several acid-related gastrointestinal conditions, including:
- Gastroesophageal Reflux Disease (GERD): A condition where acid from the stomach flows back into the esophagus, causing heartburn and irritation.
- Erosive Esophagitis (EE): Inflammation and damage to the esophagus caused by acid.
- Other Acid-Related Conditions: Your healthcare provider may also prescribe it for other conditions related to excessive stomach acid.
How to Take Dexlansoprazole
Dexlansoprazole is available in delayed-release capsules that should be swallowed whole. You can take the medication with or without food.
If you have trouble swallowing capsules, you can open them and sprinkle the contents over a spoonful of applesauce. Be sure to swallow the mixture immediately without chewing.
Recommended Dosage
- Adults: Typically, the dosage ranges from 30 mg to 60 mg once daily, depending on the condition being treated.
- Children: The use of Dexlansoprazole in children under 12 years should be monitored by a doctor.
Side Effects of Dexlansoprazole
Common Side Effects
While most people tolerate Dexlansoprazole well, some may experience mild side effects, including:
- Diarrhea
- Stomach pain
- Nausea
- Gas
- Headaches (common in children 12-17 years)
- Sore throat (common in children 12-17 years)
These effects are usually temporary and should resolve after a short time. However, if they persist, inform your healthcare provider.
Serious Side Effects
In rare cases, Dexlansoprazole may cause severe side effects. If you experience any of the following, seek immediate medical attention:
- Kidney Issues: Symptoms such as a decrease in urination or blood in urine could signal a kidney problem.
- Severe Skin Reactions: Rash, redness, and peeling skin can indicate life-threatening conditions like Stevens-Johnson Syndrome (SJS) or Toxic Epidermal Necrolysis (TEN).
- Clostridium difficile Infection: Symptoms like watery diarrhea, fever, or severe abdominal pain could signal an overgrowth of harmful bacteria in the intestines.
- Liver and Blood Disorders: A rash, fever, or difficulty breathing could indicate a serious allergic reaction such as DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms).
- Low Magnesium Levels: Prolonged use of Dexlansoprazole may cause hypomagnesemia, leading to symptoms like muscle spasms, seizures, or irregular heartbeats.
Precautions and Warnings
Before using Dexlansoprazole, it’s important to consider the following:
Who Should Avoid Dexlansoprazole?
- Allergy to Proton Pump Inhibitors (PPIs): Do not use if you are allergic to Dexlansoprazole or any other PPI.
- Kidney or Liver Disease: People with existing kidney or liver problems should consult a doctor before using this medication.
- Long-term Use: Long-term use of PPIs may increase the risk of bone fractures, low magnesium levels, and vitamin B-12 deficiency.
Drug Interactions
Dexlansoprazole may interact with the following medications:
- Methotrexate (for cancer or autoimmune conditions)
- Warfarin (a blood thinner)
- Digoxin (for heart conditions)
- HIV medications (e.g., rilpivirine)
- St. John’s Wort (an herbal supplement)
Always inform your healthcare provider about any medications or supplements you are taking before starting Dexlansoprazole.
How to Store Dexlansoprazole
Store Dexlansoprazole at room temperature, ideally between 68°F to 77°F (20°C to 25°C). It can be exposed to temperatures between 59°F to 86°F (15°C to 30°C) for short periods (e.g., during transport). Keep the medication in a cool, dry place and out of reach of children.
What Should You Do If You Miss a Dose or Overdose?
Missed Dose
If you miss a dose of Dexlansoprazole, take it as soon as you remember. If it’s close to your next dose, skip the missed one. Do not double the dose to make up for a missed one.
Overdose
In the case of an overdose, seek immediate medical attention. Symptoms of overdose may include confusion, dizziness, and nausea.
Conclusion
Dexlansoprazole is an effective and widely used medication for managing acid-related gastrointestinal conditions like GERD and erosive esophagitis.
While the drug is generally well-tolerated, it’s important to be aware of potential side effects, especially serious reactions such as kidney issues, severe skin conditions, and low magnesium levels.
Always follow your doctor’s instructions, and never hesitate to seek medical advice if you notice any unusual symptoms.
People May Ask
1. How long does it take for Dexlansoprazole to work?
Dexlansoprazole typically takes 1 to 4 days to fully relieve symptoms of GERD or esophagitis, but immediate relief is not expected.
2. Can Dexlansoprazole be taken during pregnancy?
Consult your healthcare provider before using Dexlansoprazole if you are pregnant or planning to become pregnant.
3. What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not take two doses at once.
4. Can Dexlansoprazole cause bone problems?
Long-term use of Dexlansoprazole may increase the risk of bone fractures due to reduced calcium absorption.
5. Is it safe to drink alcohol while taking Dexlansoprazole?
While there are no known interactions between alcohol and Dexlansoprazole, it’s always wise to discuss alcohol consumption with your doctor, especially if you’re on long-term treatment.
Disclaimer
The information in this article is intended for general informational purposes only and does not substitute for medical advice, diagnosis, or treatment.
Always consult with a qualified healthcare provider before starting any new medication or if you have concerns regarding your current medications.
If you experience any adverse effects, contact your healthcare provider immediately.
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