Humira, known by its generic name adalimumab, is a widely used medication in the treatment of autoimmune conditions.
As a TNF (Tumor Necrosis Factor) inhibitor, Humira works by targeting and blocking the activity of TNF, a protein in the body that plays a key role in causing inflammation.
This medication is prescribed for several conditions, primarily those involving excessive inflammation.
However, while effective, Humira comes with important considerations, including potential side effects, proper administration, and storage guidelines.
- What Is Humira Used For?
- Key Considerations Before Starting Humira
- How Humira is Administered
- Potential Side Effects of Humira
- Serious Infections
- Hepatitis B Reactivation
- Allergic Reactions
- Blood and Nervous System Issues
- Heart Failure and Liver Problems
- Other Side Effects
- How to Store Humira
- Ingredients in Humira
- Disclaimer
- Conclusion
- People May Ask
- What is the primary use of Humira?
- Can Humira cause infections?
- How do I inject Humira?
- How should Humira be stored?
- What are the side effects of Humira?
- Can I use Humira while pregnant or breastfeeding?
What Is Humira Used For?
Humira is primarily used to manage conditions that involve chronic inflammation.
It is commonly prescribed for adults with moderate to severe rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and ulcerative colitis (UC).
For children, Humira is often used in the treatment of juvenile idiopathic arthritis (JIA) and Crohn’s disease.
It can also be used to treat chronic plaque psoriasis in adults and non-infectious forms of uveitis in both children and adults.
By inhibiting the action of TNF, Humira reduces inflammation, pain, and damage caused by these diseases.
For individuals suffering from autoimmune disorders, it offers a significant improvement in quality of life by controlling symptoms and potentially inducing remission.
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Key Considerations Before Starting Humira
Before beginning treatment with Humira, it’s crucial to undergo a thorough evaluation by your healthcare provider.
This medication can influence your immune system, and it’s important to rule out infections, including tuberculosis (TB), as the drug can suppress your body’s ability to fight infections.
Patients may also need to be tested for hepatitis B and certain fungal infections, particularly if they live in or have traveled to areas where such conditions are more common.
Moreover, individuals who have experienced frequent infections, or those with a history of heart failure, may need closer monitoring during treatment.
It’s vital to inform your doctor if you have any existing conditions, including active infections, heart problems, neurological issues, or if you’re pregnant or breastfeeding.
Certain other medications, such as those used to treat other autoimmune conditions, may interact negatively with Humira.
If you’re using other TNF inhibitors or have recently been treated with chemotherapy drugs like Rituxan, it may not be safe to use Humira.
How Humira is Administered
Humira is given as an injectable medication. Depending on your condition, the dosage and frequency of injections may vary.
Your healthcare provider will guide you on how to properly administer the injections, and it’s important that you are trained in this process before taking the drug on your own.
The injection is typically administered subcutaneously (under the skin), and your doctor will let you know how often it should be given.
It’s crucial to adhere to the prescribed schedule for injections.
If you miss a dose, make sure to take it as soon as you remember, unless it’s almost time for the next dose. In that case, skip the missed dose and continue with your regular schedule.
Overdosing can also be dangerous, so it’s important to seek immediate medical attention if you suspect you’ve taken more than prescribed.
Potential Side Effects of Humira
Humira, like all medications, can cause side effects. Some of these may be mild and manageable, while others can be severe and require immediate medical attention.
Serious Infections
Since Humira suppresses the immune system, it increases the risk of serious infections. Tuberculosis (TB) is one of the most significant concerns, but other infections caused by bacteria, viruses, or fungi can also occur.
Before starting Humira, your doctor will test you for TB and monitor you regularly during treatment.
You should immediately report any signs of infection, including persistent fever, cough, or weight loss.
Hepatitis B Reactivation
If you are a carrier of hepatitis B, the virus could become reactivated while using Humira, leading to severe liver damage. Your doctor will monitor your liver function closely before, during, and after treatment with the drug.
Allergic Reactions
Humira can cause serious allergic reactions. Symptoms may include hives, difficulty breathing, or swelling of the face, lips, or throat. If you experience any of these symptoms, seek emergency medical help.
Blood and Nervous System Issues
Humira has been associated with blood disorders that can make it harder for your body to fight infections or stop bleeding. If you notice unusual bruising, paleness, or persistent fever, contact your doctor immediately. Additionally, some people experience nervous system problems, such as numbness, tingling, or weakness, which may require discontinuation of the medication.
Heart Failure and Liver Problems
Humira may worsen heart failure or contribute to new symptoms of heart failure, including shortness of breath, swelling, or sudden weight gain. Rarely, it can also cause liver problems, such as jaundice, abdominal pain, or dark urine. If any of these symptoms occur, medical attention should be sought immediately.
Other Side Effects
Some users may develop skin reactions like psoriasis or worsening of pre-existing psoriasis. Additionally, common side effects include injection site reactions (redness, swelling, pain), upper respiratory infections, and headaches.
How to Store Humira
Proper storage of Humira is essential to maintain its effectiveness. The medication should be refrigerated between 36°F and 46°F (2°C to 8°C) in its original packaging to protect it from light. I
f you need to store Humira at room temperature, it can be kept for up to 14 days at a maximum of 77°F (25°C), but it should be discarded if not used within that time.
Humira should never be frozen or stored in extreme temperatures. Always check the medication before use—do not inject if the liquid appears cloudy, discolored, or has particles in it.
Ingredients in Humira
Humira contains adalimumab as its active ingredient, which is responsible for its therapeutic effects. The inactive ingredients can include substances like mannitol, polysorbate 80, and water for injection, among others. These ingredients help maintain the stability and effectiveness of the drug during storage and use.
Disclaimer
This article is for informational purposes only and should not be considered medical advice. Always consult your healthcare provider before starting or adjusting any medication, including Humira. Individual responses to treatments can vary. For personalized advice and concerns, speak with your doctor.
Conclusion
Humira offers significant relief for individuals with autoimmune diseases, helping to control inflammation and prevent damage caused by conditions like rheumatoid arthritis, psoriasis, and Crohn’s disease.
However, like all medications, it carries potential risks.
It is essential for patients to be closely monitored during treatment and to follow their doctor’s instructions regarding administration and storage.
By doing so, the benefits of Humira can be maximized while minimizing potential side effects.
People May Ask
What is the primary use of Humira?
Humira is primarily used to treat autoimmune conditions like rheumatoid arthritis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis.
Can Humira cause infections?
Yes, Humira can suppress the immune system, making it easier for infections to occur. Your doctor will monitor you for signs of infection during treatment.
How do I inject Humira?
Humira is administered as a subcutaneous injection. You will be trained by your doctor or healthcare provider on how to give yourself the injection.
How should Humira be stored?
Humira should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). It can be kept at room temperature for up to 14 days, but should be discarded if not used within that time.
What are the side effects of Humira?
Common side effects of Humira include injection site reactions, upper respiratory infections, headaches, and rashes. Serious side effects can include infections, liver problems, heart failure, and blood disorders.
Can I use Humira while pregnant or breastfeeding?
If you’re pregnant or breastfeeding, consult your doctor to discuss the risks and benefits of using Humira during these times.
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